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Temperature of embryo culture for assisted reproduction

Tue, 09/17/2019 - 22:01
Review question Cochrane review authors reviewed the evidence for culturing human embryos at different temperatures during assisted reproduction, to analyse which strategy leads to the highest live birth rate. Background 'Infertility' is defined as the failure to achieve pregnancy after

Interventions to support women who are overweight or obese to start and continue breastfeeding

Tue, 09/17/2019 - 11:01
What is the issue? Breastfeeding is important for the health of mothers and their infants. Current advice is for exclusive breastfeeding to continue until babies are six months of age. Infants fed with formula milk are at greater risk of infections, asthma and sudden infant death syndrome. Mothers

Antibiotic treatment for spontaneous bacterial peritonitis in people with advanced liver disease

Mon, 09/16/2019 - 14:01
What is the aim of this Cochrane Review? To find out the best available antibiotic for spontaneous bacterial peritonitis (fluid collection in the tummy (abdomen), infected with bacteria) in people with advanced liver disease (liver cirrhosis, or late stage scarring of the liver with complications).

How accurate is the Mini-Cog in detecting dementia among patients in inpatient and outpatient hospital settings?

Sat, 09/14/2019 - 22:01
Why is recognising dementia important? Dementia is a common and important condition, and many of those living with dementia have never had the condition diagnosed. Diagnosis provides opportunities for social support, advance care planning and, in specific disease types, treatment with medication.

Cyclosporine A eye drops for the treatment of dry eye

Fri, 09/13/2019 - 16:01
What is the aim of this review? The aim of this Cochrane Review was to find out if cyclosporine A (CsA) eye drops are helpful in the treatment of dry eye. Cochrane researchers collected and analyzed all relevant studies to answer this question and found 30 studies. What is the key message of this

Interventions for maintaining surgically included remission in Crohn's disease

Thu, 09/12/2019 - 15:01
What is the aim of this review? The aim of this Cochrane Review was to find out which drugs are most effective for maintaining remission in people with Crohn's disease who have undergone surgery to achieve remission. We collected and analysed all relevant studies to answer this question. We

Treatment of hepatorenal syndrome

Thu, 09/12/2019 - 13:01
What is the aim of this Cochrane review? To find out the best treatment for decreased kidney function (hepatorenal syndrome) in people with liver cirrhosis (a form of advanced liver disease with scarring of the liver) with complications. The authors collected and analysed all relevant studies to

Respiratory muscle training in children and adults with neuromuscular disease

Thu, 09/05/2019 - 23:01
Review question Does respiratory muscle training have beneficial effects for children and adults with neuromuscular disease? Background Neuromuscular disease is a very broad term that covers many diseases that either directly or indirectly affect muscles or nerves. Children and adults with

Interventions for unexplained infertility: a systematic review and meta-analysis

Thu, 09/05/2019 - 10:01
Review question Researchers in Cochrane reviewed the evidence on the effectiveness and safety of ovarian stimulation (OS), intrauterine insemination (IUI), OS-IUI, and in vitro fertilisation (IVF) with or without intracytoplasmic sperm injection (ICSI) versus expectant management in couples with

Medicines to treat delirium in critically ill adult patients

Tue, 09/03/2019 - 18:01
Review question We reviewed the evidence from randomized controlled trials for the benefits and safety of all prescription medicines used to treat critically ill adult patients with delirium in the intensive care units (ICUs) of hospitals. Background Delirium is commonly associated with surgery,

Review question

Tue, 09/03/2019 - 00:01
We asked if giving radiation therapy (cancer treatment with high energy x-rays) for localized prostate cancer in fewer fractions (treatment visits for radiation) and shorter overall treatment time with a larger dose (more than 2 Gray) given each day, works as well as the usual (conventional) number

Fetal measurements for guiding the medical management of women with diabetes in pregnancy to improve outcomes for mother and baby

Mon, 09/02/2019 - 23:01
What is the issue? Diabetes during pregnancy affects between one and three in ten pregnant women (10% to 30%), and is associated with an increased risk of adverse outcomes. The baby may grow to a large size, leading to injury of the baby during birth, or the need for caesarean delivery. It is known

Flexibility exercise training for adults with fibromyalgia

Mon, 09/02/2019 - 17:01
This review summarizes the effects of flexibility exercise for adults with fibromyalgia. What problems do fibromyalgia cause? People with fibromyalgia have persistent, widespread body pain. They may also have fatigue, anxiety, depression, and sleep difficulties. What is flexibility exercise

Are smoking cessation interventions effective for quitting smoking and reducing disease activity in people with chronic inflammatory joint disease?

Mon, 09/02/2019 - 10:01
Background Tobacco smoking increases the risk of developing inflammatory joint diseases (IJDs) such as rheumatoid arthritis, where the joints are progressively damaged by the body's own immune system. Smoking may also worsen symptoms of these diseases. This review looked at whether supportive

Bathing critically ill patients with chlorhexidine to prevent hospital-acquired infections

Fri, 08/30/2019 - 12:01
What is the aim of this review? The aim of this review was to find out whether people who are critically ill in hospital should be bathed with the antiseptic chlorhexidine, in order to prevent them from developing infections. Researchers from Cochrane collected and analysed all relevant studies to

Certolizumab pegol for the treatment of active Crohn’s disease

Thu, 08/29/2019 - 16:01
Review question We reviewed the evidence about the benefits and harms of using certolizumab pegol in people with active Crohn’s disease. Background Crohn’s disease is a chronic inflammatory disease that mainly affects the gastrointestinal tract such as the small and large intestine. Common symptoms

Contact tracing methods for tuberculosis

Wed, 08/28/2019 - 21:01
What is the aim of this review? This Cochrane Review aims to establish whether any evidence is available to support the current approach to contact tracing (the process of identifying individuals exposed to an infectious case of tuberculosis), and whether alternate options could result in a higher

Surgical removal of the womb and fallopian tubes compared to surgical removal of the womb without fallopian tubes for ovarian cancer prevention

Wed, 08/28/2019 - 08:01
Review question Cochrane researchers reviewed the evidence for the effect of surgical removal of the womb (hysterectomy) together with the fallopian tubes (salpingectomy) versus hysterectomy without salpingectomy for ovarian cancer prevention. Background Ovarian cancer is the deadliest form of

Altering the availability or proximity of food, alcohol, and tobacco products to change their selection and consumption

Tue, 08/27/2019 - 09:01
Unhealthy patterns of consumption of food, alcohol, and tobacco products are important causes of ill health. Changing the availability (the range or amount of options, or both) of these products or their proximity (the distance at which they are positioned) to potential consumers could help people

Balneotherapy for chronic venous insufficiency (CVI)

Mon, 08/26/2019 - 13:01
Background Chronic venous insufficiency is a disease caused by abnormal transport of blood into the veins of the lower limbs, which means the veins cannot pump enough blood back to the heart. This condition is defined by several signs, with gnarled and enlarged veins being the most common and

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