Vena caval filters for the prevention of pulmonary embolism in people at high risk of, or with established venous thromboembolism This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the efficacy and safety of vena caval filters (VCFs) in preventing acute pulmonary embolism (APE) in people with established venous thromboembolism (VTE), or those at high risk of developing APE. This is a protocol....

Care involving families for Indigenous early childhood well-being Key messages There was a small improvement on the overall health and well-being of Indigenous children and their families when they participated in family-centred care programmes at a primary healthcare service, but we have very low confidence in the overall evidence. All studies used community engagement strategies, which is an important aspect of working with Indigenous communities. Further adequately powered studies are likely to provide better estimates of the effects of family-centred care. What is family-centred care?...

Traitement au laser de la rétinopathie drépanocytaire Problématique de la revue Quelle est l'efficacité des différentes techniques de photocoagulation au laser dans la rétinopathie proliférante liée à la drépanocytose (développement de complications menaçant la vue en raison de la croissance excessive des vaisseaux sanguins dans la partie arrière de l'œil) ? Contexte La drépanocytose est une maladie génétique qui touche de nombreux organes, dont les yeux. Le fond de l'œil (rétine) peut développer des problèmes dus à la drépanocytose. Un certain nombre de personnes atteintes de drépanocytose...

L'échoguidage est-il une bonne option pour la cathétérisation intraveineuse périphérique chez l'adulte ? Qu'est-ce que la cathétérisation intraveineuse périphérique ? La pose d'un cathéter intraveineux périphérique est l'une des procédures les plus essentielles en médecine. Elle consiste à introduire un tube fin et flexible (appelé sonde ou canule) dans une veine à l'aide d'une aiguille. Ce processus est connu sous le nom de « cathétérisation ». Il est nécessaire lors de l'administration de fluides, de médicaments et de prélèvements sanguins. La cathétérisation intraveineuse...

Exercise therapy for fatigue in multiple sclerosis This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Primary objectives The primary objectives of this review are as follows. 1.1 To determine the immediate (i.e. postintervention; 1.1a) and long-term (i.e. follow-up; 1.1b) benefits of exercise therapy, when compared to a control group, on self-reported fatigue in people with MS; and 1.2 To specifically determine the immediate and long-term benefits of exercise therapy, when compared to a control group, on self-reported fatigue when only clinical trials are...

Fluid restriction for treatment of symptomatic patent ductus arteriosus in preterm infants This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effectiveness and safety of fluid restriction for symptomatic patent ductus arteriosus (PDA) in preterm infants. To determine if fluid restriction (parenterally, enterally, or both) with or without diuretics reduces morbidity and mortality in preterm infants with a symptomatic PDA. This is a protocol....

Transarterial chemoembolisation plus I125 seeds implantation for people with unresectable hepatocellular carcinoma This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of transarterial chemoembolisation (TACE) plus I125 seeds implantation compared with TACE alone, regardless of chemotherapeutic drugs and vascular occlusive agents, for people with unresectable hepatocellular carcinoma. This is a protocol....

Is ultrasound guidance a good option for peripheral intravenous cannulation in adults? What is peripheral intravenous cannulation? Placing a peripheral intravenous line is one of the most essential procedures in medicine. It involves putting a thin, flexible tube (known as a catheter or cannula) into a vein using a needle. This process is known as 'cannulation'. It is necessary when administering fluids, drugs, and drawing blood samples. Peripheral intravenous cannulation is usually carried out by seeing and touching a target vein in the hand or arm. This is known as the landmark method....

Surgery for spontaneous supratentorial intracerebral haemorrhage This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the efficacy and safety of surgery plus standard medical management, compared to standard medical management alone, in people with spontaneous supratentorial ICH, and to assess whether the effect of surgery differs according to the surgical technique. This is a protocol....

Umbilical cord management strategies for improving outcomes in preterm infants: a network meta-analysis This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the efficacy and safety of different umbilical cord management strategies in preterm infants (before 37 weeks’ gestation), and to provide rankings of the available methods according to their effectiveness and safety profile using a network meta-analysis. This is a protocol....

Immer mehr Raucherinnen und Raucher, die mit dem Tabak aufhören wollen, wechseln zu elektrischen Zigaretten, kurz E-Zigaretten. Auf diese Weise muss man nicht auf das Ritual des Rauchens verzichten, Nikotin im Dampf kann zusätzlich über die körperlichen Entzugserscheinungen hinweghelfen. Ein …

Dampfen statt Rauchen: E-Zigaretten zur Rauchentwöhnung ARTIKEL LESEN

Der Beitrag Dampfen statt Rauchen: E-Zigaretten zur Rauchentwöhnung erschien zuerst auf Wissen Was Wirkt.

Chez les prématurés, quelle est la précision des tests sanguins BNP et NT-proBNP pour identifier les canaux artériels persistants qui nécessitent un traitement supplémentaire ? Un certain nombre de prématurés présentent un problème cardiaque appelé canal artériel persistant (CAP). Un CAP est un vaisseau sanguin qui se ferme généralement spontanément chez les enfants à terme et la plupart des prématurés, mais chez certains, le CAP a tendance à rester ouvert plus longtemps. Les prématurés qui ont un CAP ouvert restent souvent stables, mais chez certains d'entre eux, le flux sanguin important...

Ajout d'un anneau gastrique (fundoplicature) autour du tube alimentaire (œsophage) dans le cadre d'une chirurgie mini-invasive (laparoscopique) pour traiter l'achalasie Problématique de la revue 1) L'ajout d'un anneau gastrique autour du tube digestif (œsophage) réduit-il le reflux des aliments et de l'acide de l'estomac vers le tube digestif (régurgitation) lorsqu'il est utilisé avec la chirurgie mini-invasive pour traiter l'achalasie ? 2) Quel type d'enroulement de l'estomac (partiel ou total) autour du tube digestif est le plus efficace pour contrôler les régurgitations...

Interventions for unresectable intrahepatic cholangiocarcinoma: a network meta-analysis This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To establish the existence of differences in effectiveness and safety of intra-arterial therapies (IATs) such as bland embolisation, conventional transarterial chemoembolisation (cTACE), drug-eluting bead transarterial chemoembolisation (DEBTACE), yttrium-90 (Y90), hepatic artery infusion (HAI), external beam radiotherapies (EBRTs), and immunotherapy versus systemic chemotherapy for unresectable intrahepatic...

Addition of a stomach wrap (fundoplication) around the food pipe (oesophagus) in keyhole (laparoscopic) surgery to treat achalasia Review questions 1) Does the addition of a stomach wrap around the food pipe (oesophagus) reduce the backflow of food and acid from the stomach to the food pipe (regurgitation) when used with keyhole surgery to treat achalasia? 2) Which type of stomach wrap (partial or total) around the food pipe is better at controlling regurgitation without causing difficulty in swallowing (dysphagia) when used with keyhole surgery to treat achalasia? Background Achalasia is a...

Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with and without prior cognitive impairment This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Primary objective To assess the efficacy and safety of anticholinergic medication reduction interventions to improve cognitive outcomes in both cognitively healthy older adults and older adults with pre-existing cognitive issues. Secondary objectives To compare the effectiveness of different types of reduction interventions (e.g. pharmacist-led versus...

In preterm infants, how accurate are the blood tests BNP and NT-proBNP in identifying PDAs (patent ductus arteriosus) that require further treatment? A number of preterm infants have a heart condition called patent ductus arteriosus (PDA). A PDA is a blood vessel that usually closes spontaneously in term and most preterm infants, but in some the PDA tends to remain open longer. Preterm infants who have an open PDA often remain stable; but in some, the large blood flow through the PDA can cause breathing and blood pressure problems and may need treatment. Usually, a large PDA is identified by...

In this blog, Sarah Chapman looks at the new evidence from Cochrane on COVID-19 vaccines.

The post Are COVID-19 vaccines effective and safe? New Cochrane evidence appeared first on Evidently Cochrane.

Utilisation de dispositifs de réparation des nerfs dans le bras, l'avant-bras et la main Qu'est-ce qu'une lésion nerveuse et comment est-elle réparée ? Les lésions des nerfs du bras, de l'avant-bras et de la main sont fréquentes et ont un effet durable sur la capacité de mouvement et les sensations d'une personne. En général, les chirurgiens aboutent et suturent les nerfs blessés (une réparation standard). Parfois, ils utilisent également une greffe de nerf, c'est-à-dire qu'ils prélèvent un nerf dans une autre partie du corps pour combler l'espace entre les extrémités d'un nerf...

Welchen Nutzen und welche Risiken haben die verfügbaren Impfstoffe zur Vorbeugung von COVID-19? Kernaussagen - Die meisten Impfstoffe verringern (oder verringern wahrscheinlich) sowohl die Zahl der Menschen, die an COVID-19 erkranken als auch die Zahl derjenigen, die schwer an COVID-19 erkranken. - Bei vielen Impfstoffen ist es wahrscheinlich, dass im Vergleich zu einer Placebo-Impfung (die keinen Wirkstoff enthält, aber genauso aussieht wie der untersuchte Impfstoff) bei mehr Personen Ereignisse wie Fieber oder Kopfschmerzen auftreten. Diese Ereignisse sind zu erwarten und sind im...