En bloc versus standard transurethral resection of bladder tumors for non-muscle-invasive bladder cancer patients This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of en bloc resection compared with conventional transurethral resection of the bladder tumor (conventional TURBT) in patients with non-muscle-invasive bladder cancer. This is a protocol....

Volatile pyrethroid spatial repellents for malaria prevention This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effectiveness of volatile pyrethroid spatial repellents (VPSRs) for preventing new cases of Plasmodium falciparum and Plasmodium vivax malaria. This is a protocol....

Drug treatments for the prevention of attacks of hereditary angioedema What is hereditary angioedema and how is it treated? Hereditary angioedema (HAE) is a serious and potentially life-threatening condition that causes acute (sudden onset) attacks of swelling, pain and reduced quality of life. Several new medicines have been developed to treat acute attacks and prevent attacks from occurring. Some medicines are taken by mouth, whereas others are injected under the skin, or given by a vein directly into the blood. The medicines currently given for preventing HAE attacks are human C1 esterase...

Immunomodulators and immunosuppressants for progressive multiple sclerosis: a network meta-analysis This is a protocol for a Cochrane Review (intervention). The objectives are as follows: We will perform a network meta-analysis to assess the relative effectiveness and safety of immunomodulatory and immunosuppressive treatments for people with multiple sclerosis in progressive forms of the condition. This is a protocol....

Prognostic factors for predicting progression of open angle glaucoma in adults This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: Primary objective To identify prognostic risk factors for progression of functional visual outcomes of primary open angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXFG) in adults. Table 1. PICOTS of the primary objective Population Adults ≥ 18 years of age of any ethnicity with open angle glaucoma (restricted to POAG and PXFG types) diagnosed as having open angle and evidence of glaucomatous damage. We will exclude studies...

Interventions for preventing haemodialysis dysequilibrium syndrome This is a protocol for a Cochrane Review (intervention). The objectives are as follows: This review aims to look at the benefits and harms of interventions for preventing HD DDS. This is a protocol....

Traitement médicamenteux des affections inflammatoires de l'œil Quel était l’objectif de la revue ? Dans cette revue systématique, nous avons étudié les données probantes disponibles sur l'efficacité et la sécurité de plusieurs médicaments utilisés pour traiter un sous-ensemble spécifique d'affections inflammatoires de la partie postérieure de l'œil. Principaux messages Nous avons constaté que le médicament méthotrexate serait légèrement plus efficace que le mycophénolate. Autrement, il n'y avait pas de données probantes solides suggérant qu'un médicament est plus efficace ou plus sûr...

Effects of different weight loss programmes on oncological outcomes following curative resection of digestive tract cancers This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effect of different weight loss programmes on oncological outcomes following curative resection of GI tract cancers. This is a protocol....

Interventions for improving adherence to dietary salt and fluid restrictions in people with chronic kidney disease (stage 4 and 5) This is a protocol for a Cochrane Review (intervention). The objectives are as follows: This review aims to look at the benefits and harms of non-pharmacological interventions to improve adherence to dietary salt and fluid restriction in people with CKD (stages 4 and 5). This is a protocol....

Health policymakers’ views and experiences of knowledge translation approaches to facilitate evidence-informed decision-making: a qualitative evidence synthesis This is a protocol for a Cochrane Review (qualitative). The objectives are as follows: The aim of this review is to synthesise the qualitative evidence on health policymakers’ views and experiences of knowledge translation approaches to facilitate evidence-informed decision-making. The specific objectives are to: explore health policymakers’ views and experiences of knowledge translation approaches to facilitate evidence-informed...

Treatment of inflammatory conditions of the eye with medications What was the aim of this review? In this systematic review, we studied the available evidence on the effectiveness and safety of several medications used to treat a specific subset of inflammatory conditions of the back part of the eye. Key message We found that the medication methotrexate may be slightly more effective than mycophenolate. Otherwise, there was no strong evidence to suggest one medication is more effective or safe than the others. What did we study in this review? Non-infectious intermediate, posterior, and...

In a blog for healthcare professionals Dr James Garrard, Registrar in Geriatric Medicine, looks at the importance of recognising frailty in older adults and the latest evidence on Comprehensive Geriatric Assessment.

The post Recognising and managing frailty in older adults appeared first on Evidently Cochrane.

In a blog for anyone interested in male infertility research, Astrid Cantineau, specialist in reproductive medicine, looks at the problem of poor evidence for treatments for male infertility and how the COMMIT project is working to change this.

The post Male infertility: what is an important outcome? appeared first on Evidently Cochrane.

Est-il préférable d'insérer un implant ou un dispositif intra-utérin (stérilet) pour la contraception dans les jours qui suivent l'accouchement ou d'attendre 4 à 6 semaines ? Lorsque nous utilisons le terme « personnes » dans ce résumé, nous entendons des individus ayant la capacité actuelle de devenir enceintes. Principaux messages - L'insertion d'implants contraceptifs ou de dispositifs intra-utérins (DIU) dans les jours qui suivent l'accouchement (insertion immédiate, à l'hôpital), plutôt que d'attendre 4 à 6 semaines pour les insérer (insertion différée), augmente le...

Ist es besser, ein Verhütungsimplantat oder eine Spirale innerhalb weniger Tage nach der Geburt oder 4 bis 6 Wochen später einzusetzen? Der folgend verwendete Begriff „Personen" bezieht sich auf Frauen, die derzeit schwanger werden können. Kernaussagen - Das Einsetzen von Verhütungsimplantaten oder Intrauterinpessaren (IUPs) innerhalb weniger Tage nach der Geburt (sofortiges Einsetzen, während des Krankenhausaufenthalts), anstatt 4 bis 6 Wochen später (verzögertes Einsetzen), erhöht die Zahl der Personen, denen ein solches Verhütungsmittel eingesetzt wird. - Der Zeitpunkt des Einsetzens hat...

Interventions for maintenance therapy for granulomatosis with polyangiitis and microscopic polyangiitis This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of different immunosuppressive treatments used for maintenance therapy in people who have granulomatosis with polyangiitis and microscopic polyangiitis. This is a protocol....

Unterstützung für stillende Mütter Worum geht es? Die Weltgesundheitsorganisation empfiehlt, Säuglinge in den ersten sechs Lebensmonaten ausschliesslich zu stillen und bis zum Alter von zwei Jahren Stillen als wichtigen Teil der kindlichen Ernährung beizubehalten. Wir wissen, dass Stillen sich kurzfristig und langfristig positiv auf die Gesundheit von Säuglingen und ihren Müttern auswirkt. Bei gestillten Babys ist die Wahrscheinlichkeit, dass sie Lungen- oder Darminfektionen entwickeln, geringer. Sie haben auch ein geringeres Risiko, übergewichtig zu werden und später an Diabetes zu...

Soutien aux mères allaitantes Quelle est la question ? L'Organisation mondiale de la santé recommande que les nourrissons soient exclusivement allaités jusqu'à l'âge de six mois, avec une poursuite de l'allaitement jusqu'à l'âge de deux ans au moins en tant qu’élément central du régime alimentaire. Nous savons que l'allaitement maternel est bon pour la santé à court et à long terme du nourrisson et de la mère. Les bébés sont moins susceptibles de développer des infections pulmonaires ou intestinales. Ils sont également moins susceptibles d’être en surpoids et de développer un diabète plus...

Personal protective equipment for preventing asbestos exposure in workers This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of personal protective equipment, including donning and doffing procedures and individual hygienic behaviour, compared to no such equipment or alternative equipment, on asbestos exposure in workers exposed to asbestos in demolition and repair work. This is a protocol....

In this blog for people wanting to stop smoking, Robert Walton, a very general practitioner, looks at Cochrane evidence to help you start your new smoke-free life. 

The post How to stop smoking: a look at the Cochrane evidence appeared first on Evidently Cochrane.