Eiweißarme Diäten für Erwachsene mit diabetischer Nierenerkrankung Worum geht es? Für Menschen mit diabetischer Nierenerkrankung, die nicht dialysepflichtig sind, kann es empfehlenswert sein, die Eiweißmenge in der Ernährung zu begrenzen, um das Fortschreiten der chronischen Nierenerkrankung zu verlangsamen. Es besteht jedoch nach wie vor Unsicherheit darüber, wie viel Eiweiß man zu sich nehmen sollte. Wie gingen wir vor? Wir haben Erkenntnisse über die Auswirkungen einer eiweißarmen Ernährung auf das Fortschreiten der Nierenerkrankung bei erwachsenen, nicht dialysepflichtigen Patient*innen...

Non-medicine interventions for sleep problems in dementia What are sleep problems in people with dementia? People with dementia frequently have sleep problems including an increase in the length and number of awakenings and an increased amount of light sleep. These cause a number of problems for the affected person, their relatives, and carers, possibly leading to carer distress and the admission of people with dementia to nursing homes or long-term care homes. Can non-medicine interventions help? As we do not know if medicines can help improve sleep in people with dementia, non-medicine...

Methods of induction of labour: a network meta-analysis This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To compare the effectiveness and safety profiles for the different methods of cervical ripening and labour induction at or beyond term labour using network meta-analysis, and to provide rankings of the available treatments according to their effectiveness and safety profile. This is a protocol....

Low protein diets for adults with diabetic kidney disease What is the issue? For people with diabetic kidney disease (DKD) not requiring dialysis, it may be recommended to limit the amount of protein in the diet to slow the progression of chronic kidney disease. However, uncertainty remains about how much protein should be consumed. What did we do? We reviewed the evidence about the effect of low protein diets on the progression of kidney disease in adult patients with DKD, not on dialysis. The evidence is current to 17 November 2022. All studies were combined, provided that they compared a...

What are the benefits and risks of silicone gel sheeting for treating keloid scars? Key messages We are uncertain whether silicone gel sheeting improves a scar's appearance more than: - no treatment; - treatment with a dressing similar to silicone gel sheeting that does not contain silicone; - injections of triamcinolone acetonide (a medication) directly into a lesion or below the skin. We are uncertain about the effect of silicone gel sheeting on pain compared with no treatment. We do not know if silicone gel sheeting has an effect on pain compared with non-silicone gel sheeting or...

Sarah Chapman revisits a blog by occupational therapist Danny Minkow on static splinting for people after stroke, adding recent evidence and guidance.

The post Static splinting after stroke: evidence and practice appeared first on Evidently Cochrane.

Gerade wenn es um Krebs geht, scheint das Motto „Früh erkannt, Gefahr gebannt“, oder noch besser „Vorsorgen ist besser als Heilen“ wie eine Selbstverständlichkeit. Doch ist man damit wirklich immer auf der sicheren Seite? In der ersten Folge unserer neuen …

Vorsorge, Früherkennung, Screening – Kann man dem Krebs zuvorkommen? ARTIKEL LESEN

Der Beitrag Vorsorge, Früherkennung, Screening – Kann man dem Krebs zuvorkommen? erschien zuerst auf Wissen Was Wirkt.

Sarah Chapman looks at Cochrane evidence and NICE guidance on managing osteoarthritis

The post Managing osteoarthritis: evidence and guidance appeared first on Evidently Cochrane.

Halb Deutschland hustet, schnieft und fiebert; Medikamente werden knapp: Erkältungskrankheiten grassieren dieses Jahr wie schon lange nicht mehr. Am besten also erst gar nicht krank werden. Vermeintliche Geheimtipps für die Vorbeugung und Behandlung von Erkältungen gibt es im Internet genug. …

Unheilbar, aber halb so schlimm: Erkältungen und was man dagegen tun kann ARTIKEL LESEN

Der Beitrag Unheilbar, aber halb so schlimm: Erkältungen und was man dagegen tun kann erschien zuerst auf Wissen Was Wirkt.

C-reactive protein, procalcitonin, and erythrocyte sedimentation rate for the diagnosis of lower urinary tract infection in older people This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows: Secondary objectives To assess the influence of patient and study characteristics on the diagnostic accuracy of the index tests. To assess the influence of different reference standards for UTI on the diagnostic accuracy of the index tests. This is a protocol....

In the final Evidently Cochrane blog of the year, Sarah Chapman from Cochrane UK takes a look back at some highlights and changes from 2022.

The post Evidently Cochrane 2022: a look back at a year of blogs appeared first on Evidently Cochrane.

In a blog for people taking statins, or considering taking them, Dr Paula Byrne, Researcher at Evidence Synthesis Ireland, shares what she and her team found when they looked at the evidence on statins and the risk of bad outcomes like stroke and heart attack.

The post Are cholesterol-lowering statins as good as we think? appeared first on Evidently Cochrane.

Quels sont les bénéfices des AINS pour traiter l'accumulation de liquide dans la rétine centrale (macula) après une opération de la cataracte ? Principaux messages • Nous avons mis à jour les données probantes sur les effets des anti-inflammatoires non stéroïdiens (AINS, comme l'ibuprofène) chez les personnes présentant une accumulation aiguë ou chronique de liquide dans la rétine centrale (macula) après une chirurgie de la cataracte. • Il n'y avait que des données probantes d’un niveau de confiance très faible suggérant que les AINS pouvaient améliorer la vision ou réduire...

Corticoïdes inhalés pour les maladies pulmonaires chez les nouveau-nés Qu'est-ce que la dysplasie broncho-pulmonaire et comment la traiter ? Les enfants nés prématurément risquent de développer une affection pulmonaire chronique appelée dysplasie broncho-pulmonaire (DBP). L'inflammation dans le poumon prématuré semble jouer un rôle important dans le développement de la DBP. Les études ont montré que les médicaments qui suppriment l'inflammation (corticoïdes) injectés dans la circulation sanguine réduisent le risque de DBP, mais pourraient aussi avoir des effets secondaires graves sur...

Quels sont les bénéfices et les risques du paracétamol (acétaminophène) en cas de canal artériel persistant (CAP, un vaisseau sanguin nécessaire à la survie du fœtus) chez les prématurés et les nourrissons de faible poids de naissance ? Contexte Le canal artériel persistant (CAP) est une complication fréquente chez les bébés nés avant terme (prématurés) ou de petit poids. La circulation sanguine vers les poumons (encore) non fonctionnels est inutile avant la naissance. Cela s'explique par le fait que le placenta fournit de l'oxygène au sang du fœtus. Le CAP est un vaisseau sanguin fœtal...

LipiFlow for the treatment of dry eye disease This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the effectiveness of the LipiFlow Thermal Pulsation System on dry eye signs and symptoms compared to placebo or other commercially available treatments for meibomian gland dysfunction in adults. This is a protocol....

First aid training for laypeople This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Main objective To assess the effects of first aid training for laypeople, compared to no training or other training on: (1) the helping behaviour of the persons providing first aid, (2) the quality of the first aid provided, and (3) the health outcomes of the people receiving first aid. Secondary objectives To assess the effects of first aid training for laypeople on first aid-related knowledge, skills, self-efficacy, willingness to help, and adverse effects. This is a...

Les vaccins dans la prévention du rhume Problématique de la revue Les vaccins peuvent-ils aider à prévenir le rhume ? Contexte Le rhume est principalement causé par une infection virale des voies respiratoires supérieures. Les personnes atteintes du rhume se sentent mal, ont le nez qui coule, une congestion nasale, des éternuements, une toux avec ou sans mal de gorge et une température légèrement élevée. Cependant, les personnes se rétablissent généralement lorsque leur système immunitaire contrôle l'impact de l'infection virale. Le traitement de cette affection vise à soulager les...

Adverse events associated with minimally invasive glaucoma surgeries (MIGS) including bleb-forming microstent surgeries This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To obtain a comprehensive review of harms following MIGS reported in randomised and non-randomised studies, clinical study reports submitted to regulatory organisations for approval or postmarketing surveillance and registries. We will also examine the design characteristics, risk of bias, and reporting adequacy of pivotal MIGS trials submitted to the US and EU regulatory organisations...

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms, including pain, discomfort, and success rate, of any pharmacological intervention during lumbar puncture in newborn infants, compared to placebo, no intervention, non-pharmacological interventions, or other pharmacological interventions. This is a protocol....